Finding new treatments for neurofibromatosis type 2
Employing functionalized fragment libraries to identify therapeutic agents for neurofibromatosis type 2
This study is looking for new treatments for neurofibromatosis type 2 (NF2) by testing different compounds in a way that closely resembles how cells actually work in the body, with the hope of finding better options for managing tumors related to this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-10848388 on NIH RePORTER |
What this research studies
This research focuses on neurofibromatosis type 2 (NF2), a genetic condition that leads to the development of tumors in the nervous system. The team aims to identify new therapeutic agents by using advanced techniques that better mimic the natural environment of cells, rather than traditional methods that may not accurately reflect how cells behave in the body. By screening a diverse library of compounds, the researchers hope to discover effective treatments that target NF2-related tumors more selectively. This approach could lead to significant advancements in managing the condition and improving patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with neurofibromatosis type 2, particularly those experiencing tumor growth.
Not a fit: Patients without a diagnosis of neurofibromatosis type 2 or those with other unrelated conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide new, more effective treatment options for patients with neurofibromatosis type 2.
How similar studies have performed: While there have been limited successes in identifying treatments for NF2, this approach is innovative and aims to overcome previous challenges faced in similar research.
Where this research is happening
Tampa, United States
- H. Lee Moffitt Cancer Ctr & Res Inst — Tampa, United States (Active)
Researchers
- Principal investigator: Kissil, Joseph — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Kissil, Joseph
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.