Finding new treatments for lung infections caused by non-tuberculous mycobacteria.
Discovery of Novel Nontuberculous Inhibitors
['FUNDING_R15'] · CREIGHTON UNIVERSITY · NIH-10291635
This study is looking for new antibiotics to help people with lung diseases like cystic fibrosis and bronchiectasis fight off tough infections caused by non-tuberculous mycobacteria, and you might have a chance to join trials testing these promising new treatments that could work better and have fewer side effects than what’s currently available.
Quick facts
| Phase | ['FUNDING_R15'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CREIGHTON UNIVERSITY (nih funded) |
| Locations | 1 site (OMAHA, UNITED STATES) |
| Trial ID | NIH-10291635 on ClinicalTrials.gov |
What this research studies
This research focuses on developing new antibiotics to combat infections caused by non-tuberculous mycobacteria (NTM), which are increasingly affecting patients with lung diseases like cystic fibrosis and bronchiectasis. The team has identified a new class of compounds that show promise in effectively inhibiting these pathogens. By testing these compounds, the research aims to find treatments that are more effective and have fewer side effects than current therapies. Patients may have the opportunity to participate in trials that evaluate the safety and efficacy of these novel treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with chronic lung diseases, particularly those infected with non-tuberculous mycobacteria.
Not a fit: Patients without lung diseases or those not infected with non-tuberculous mycobacteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients suffering from difficult-to-treat lung infections.
How similar studies have performed: Previous research has shown promise in developing new antibiotics for similar infections, indicating that this approach may yield beneficial results.
Where this research is happening
OMAHA, UNITED STATES
- CREIGHTON UNIVERSITY — OMAHA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NORTH, ELTON JEFFREY — CREIGHTON UNIVERSITY
- Study coordinator: NORTH, ELTON JEFFREY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.