Finding new treatments for chronic nerve pain
Discovery and development of novel glycine transporter-2 inhibitors for the treatment of neuropathic pain
This study is looking for new ways to help people with chronic nerve pain by creating medications that boost the body's natural pain relief, and if you're interested, you might have a chance to join a trial to test these new treatments!
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rensselaer Polytechnic Institute NIH-funded |
| Lab location | 1 site (Troy, United States) |
| Project ID | NIH-10592522 on NIH RePORTER |
What this research studies
This research focuses on developing new medications to treat chronic neuropathic pain, which affects a significant portion of the population. It aims to enhance the body's natural pain relief mechanisms by targeting a specific transporter in the brain that regulates pain signaling. By creating inhibitors of the glycine transporter-2, the research seeks to improve pain relief while minimizing side effects and the risk of addiction associated with current pain medications. Patients may have the opportunity to participate in clinical trials testing these novel treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who experience chronic neuropathic pain.
Not a fit: Patients with acute pain conditions or those who do not experience neuropathic pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective pain relief options for patients suffering from chronic neuropathic pain.
How similar studies have performed: Previous research has shown promise in using glycine transporter inhibitors for pain relief, indicating a potential for success in this approach.
Where this research is happening
Troy, United States
- Rensselaer Polytechnic Institute — Troy, United States (Active)
Researchers
- Principal investigator: Cioffi, Christopher L. — Rensselaer Polytechnic Institute
- Study coordinator: Cioffi, Christopher L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.