Finding New Treatments for Childhood Sarcoma and Rare Cancers
Official title: Pediatric Preclinical In Vivo Testing Center for Pediatric Sarcoma and Other Solid Tumors
Funded at Sloan-Kettering Inst Can Research · NIH-11109395 · Data updated 2026-11-12
This work aims to discover new drug options for children facing sarcomas and other rare solid tumors.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 1, 2021 |
| Project end | June 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $727,406 |
| NIH project number | 5U01CA263967-05 |
| Project ID | NIH-11109395 on NIH RePORTER |
Who could benefit from this research
✓Could help
This research is ultimately for children diagnosed with pediatric bone and soft tissue sarcomas, renal tumors, desmoplastic small round cell tumor (DSRCT), and other rare pediatric solid tumors.
✕Less likely to help
Patients not diagnosed with pediatric sarcomas or other rare solid tumors would not directly benefit from this specific preclinical research.
What this research studies
Our team has developed over 300 models using tumor samples from children with solid tumors, which helps us understand how different cancers behave. We use these models to test many existing and new cancer drugs to see which ones might work best. The goal is to identify promising treatments that can then be further explored in clinical trials for children. This approach helps us quickly find the most effective drugs for specific types of pediatric cancers.
Why it matters
Potential benefit: If successful, this work could lead to new and more effective treatment options for children with difficult-to-treat sarcomas and other rare solid tumors.
How similar studies have gone: This program builds upon an established preclinical testing program that has successfully created a large collection of patient-derived models for pediatric solid tumors.
Where this research is happening
-
Sloan-Kettering Inst Can Research
New York, United States Active
Researchers
- Principal investigator: Kung, Andrew L — Sloan-Kettering Inst Can Research
- Study coordinator: Kung, Andrew L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.