Finding new treatments for bile duct cancer

Identifying therapeutic options for intrahepatic cholangiocarcinoma

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-11053521

This study is looking at bile duct cancer to find specific markers in the genes and proteins that could help create better treatments for patients, making it easier to fight this tough disease.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-11053521 on NIH RePORTER

What this research studies

This research focuses on intrahepatic cholangiocarcinoma (ICC), a type of bile duct cancer with a very low survival rate. The team is investigating the genetic and molecular characteristics of ICC to identify specific biomarkers that can help tailor treatments for patients. By studying how certain proteins and genes interact in cancer cells, they aim to develop targeted therapies that could improve patient outcomes. The research involves analyzing patient samples and using advanced genetic techniques to understand the disease better.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with intrahepatic cholangiocarcinoma.

Not a fit: Patients with other types of cancer or those without a diagnosis of intrahepatic cholangiocarcinoma may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective, personalized treatment options for patients with bile duct cancer.

How similar studies have performed: Other research has shown promise in identifying targeted therapies for various cancers, suggesting that this approach could also be effective for intrahepatic cholangiocarcinoma.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions biliary cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.