Finding new treatments for Alzheimer's disease using existing data
Repurpose open data to discover therapeutics for understudied diseases
This study is looking for new treatment options for Alzheimer's disease by using existing data about genes and cancer drugs, hoping to find helpful insights that could lead to better therapies for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michigan State University NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project ID | NIH-10713005 on NIH RePORTER |
What this research studies
This research aims to repurpose existing open data to discover new therapeutic options for Alzheimer's disease and its subtypes. By integrating gene expression profiles from various disease samples with drug-induced profiles from cancer cell lines, the researchers hope to identify potential new treatments. The approach involves advanced deep learning methods and a centralized informatics system to streamline the analysis of diverse datasets. Patients may benefit from insights gained into disease mechanisms and the identification of new therapeutic candidates.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or its subtypes.
Not a fit: Patients with other forms of dementia unrelated to Alzheimer's may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for patients with Alzheimer's disease.
How similar studies have performed: Previous research has successfully utilized similar approaches to identify new therapeutic candidates for various cancers, indicating potential for success in this area as well.
Where this research is happening
East Lansing, United States
- Michigan State University — East Lansing, United States (Active)
Researchers
- Principal investigator: Chen, Bin — Michigan State University
- Study coordinator: Chen, Bin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.