Finding new non-addictive pain relief from human nerve cells
High content analgesic screening from human nociceptors
['FUNDING_OTHER'] · UNIVERSITY OF TEXAS DALLAS · NIH-11114128
This study is looking for new, non-addictive pain relief options to help people with severe pain by testing natural substances on human cells, so we can find better and safer treatments for everyone.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS DALLAS (nih funded) |
| Locations | 1 site (RICHARDSON, UNITED STATES) |
| Trial ID | NIH-11114128 on ClinicalTrials.gov |
What this research studies
This research focuses on developing new, non-addictive analgesics to effectively treat severe acute and chronic pain. The approach involves screening natural product fractions using human sensory neurons to better understand pain mechanisms and identify potential new pain relief options. By utilizing human cells instead of animal models, the research aims to improve the translation of findings to human patients, addressing the limitations of current analgesic screening methods. This innovative methodology seeks to enhance the efficacy and safety of pain management therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from severe acute or chronic pain who are seeking alternative pain management options.
Not a fit: Patients who do not experience pain or have conditions unrelated to pain management may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of safer pain relief medications that do not carry the risk of addiction.
How similar studies have performed: Other research has shown promise in using human cells for drug screening, indicating that this approach could yield significant advancements in pain management.
Where this research is happening
RICHARDSON, UNITED STATES
- UNIVERSITY OF TEXAS DALLAS — RICHARDSON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KOLBER, BENEDICT J — UNIVERSITY OF TEXAS DALLAS
- Study coordinator: KOLBER, BENEDICT J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.