Finding new natural antibiotics to fight resistant infections
Official title: Scalable discovery of saccharide natural products using high-throughput multi-omics
Funded at Chemia Biosciences, INC. · NIH-11004018 · Data updated 2026-11-12
This study is looking for new natural antibiotics to help fight infections that are becoming harder to treat because of antibiotic resistance, and it's for anyone who might be affected by these tough-to-treat infections.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Chemia Biosciences, INC. NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | September 5, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $317,029 |
| NIH project number | 1R43TR005259-01 |
| Project ID | NIH-11004018 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients suffering from infections caused by antibiotic-resistant bacteria, such as pneumonia, tuberculosis, or blood poisoning.
✕Less likely to help
Patients with infections that are already effectively treated with existing antibiotics may not benefit from this research.
What this research studies
This research focuses on discovering new natural antibiotics to combat the growing problem of antibiotic resistance, which affects millions of patients globally. By utilizing advanced technologies like high-throughput mass spectrometry and genome mining, the team aims to predict the molecular products of gene clusters responsible for antibiotic production in microbes. This innovative approach seeks to identify novel antibiotics that can effectively target resistant pathogens, potentially leading to new treatment options for serious infections.
Why it matters
Potential benefit: If successful, this research could lead to the development of new antibiotics that are effective against drug-resistant infections, improving treatment outcomes for patients.
How similar studies have gone: Other research has shown promise in discovering new antibiotics through innovative technologies, indicating that this approach could yield significant results.
Where this research is happening
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Chemia Biosciences, INC.
Pittsburgh, United States Active
Researchers
- Principal investigator: Behsaz, Bahar — Chemia Biosciences, INC.
- Study coordinator: Behsaz, Bahar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.