Finding new natural antibiotics to fight resistant infections

Scalable discovery of saccharide natural products using high-throughput multi-omics

NIH-funded research Chemia Biosciences, INC. · NIH-11004018

This study is looking for new natural antibiotics to help fight infections that are becoming harder to treat because of antibiotic resistance, and it's for anyone who might be affected by these tough-to-treat infections.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionChemia Biosciences, INC. NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-11004018 on NIH RePORTER

What this research studies

This research focuses on discovering new natural antibiotics to combat the growing problem of antibiotic resistance, which affects millions of patients globally. By utilizing advanced technologies like high-throughput mass spectrometry and genome mining, the team aims to predict the molecular products of gene clusters responsible for antibiotic production in microbes. This innovative approach seeks to identify novel antibiotics that can effectively target resistant pathogens, potentially leading to new treatment options for serious infections.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients suffering from infections caused by antibiotic-resistant bacteria, such as pneumonia, tuberculosis, or blood poisoning.

Not a fit: Patients with infections that are already effectively treated with existing antibiotics may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of new antibiotics that are effective against drug-resistant infections, improving treatment outcomes for patients.

How similar studies have performed: Other research has shown promise in discovering new antibiotics through innovative technologies, indicating that this approach could yield significant results.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.