Finding new mosquito repellents to prevent disease transmission

Identification of powerful repellents that target mosquito olfaction, gustation and the Na-channel

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA RIVERSIDE · NIH-11028252

This study is working on creating new mosquito repellents that are better at keeping mosquitoes away from people, especially in tropical areas, to help prevent diseases like malaria and dengue.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA RIVERSIDE (nih funded)
Locations1 site (RIVERSIDE, UNITED STATES)
Trial IDNIH-11028252 on ClinicalTrials.gov

What this research studies

This research focuses on developing innovative mosquito repellents that target the sensory systems mosquitoes use to detect humans. By utilizing advanced AI-based methods, the team aims to identify new compounds that can effectively repel mosquitoes and reduce the risk of diseases like malaria and dengue. The approach involves screening millions of chemical compounds to find those that can be effective in real-world applications, especially in tropical regions where current repellents are underused due to cost and convenience issues. The goal is to create safer and more effective alternatives to existing repellents.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living in tropical regions who are at risk of mosquito-borne diseases.

Not a fit: Patients who do not live in areas with high mosquito populations or those who are not at risk for mosquito-borne diseases may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of more accessible and effective mosquito repellents, significantly reducing the incidence of mosquito-borne diseases.

How similar studies have performed: Previous research has shown promise in using AI and cheminformatics to identify new chemical compounds, indicating that this approach could yield successful results.

Where this research is happening

RIVERSIDE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.