NIH-funded research R01 grant

Finding New Medicines from Special Bacteria

Official title: Expansion and application of synthetic biology tools for natural products discovery from myxobacteria

Funded at University of Mississippi · NIH-11141744 · Data updated 2026-11-12

This project aims to discover new medicines, especially for fighting bacteria and viruses, by exploring unique compounds found in certain types of bacteria.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Mississippi
NIH-funded
Lab location1 site (University, United States)
Project startAugust 1, 2024
Project endJune 30, 2028
Funding year2025
Award (this year)$289,424
NIH project number5R01GM149795-02
Project IDNIH-11141744 on NIH RePORTER

Who could benefit from this research

Could help

Future patients suffering from bacterial or viral infections could potentially benefit from new treatments developed as a result of this foundational research.

Less likely to help

Patients seeking immediate treatment options or direct clinical participation will not find this basic science project directly applicable to their current care.

What this research studies

Many important medicines come from natural sources, especially from bacteria. This project uses advanced genetic tools, called synthetic biology, to unlock the potential of a special group of bacteria called myxobacteria. Researchers want to expand the methods available to study these bacteria, which are known for producing unique compounds different from other bacteria. By developing new ways to grow and analyze these myxobacteria, scientists hope to uncover novel natural products that could become future drugs.

Why it matters

Potential benefit: If successful, this work could lead to the discovery of entirely new antibacterial and antiviral medications, offering new hope for treating difficult infections.

How similar studies have gone: Similar synthetic biology approaches have already been successful in discovering new active compounds from other types of bacteria, showing promise for this expanded effort.

Where this research is happening

  • University of Mississippi
    University, United States
    Active

Researchers

  • Principal investigator: Stevens, David Cole — University of Mississippi
  • Study coordinator: Stevens, David Cole

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.