Finding New Medicines for Malaria
Optimization of novel phenotypic screening hits for treatment of Malaria
['FUNDING_R01'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-11059861
This project is looking for brand new medicines to fight malaria, a serious disease that affects many people, especially young children in Africa.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-11059861 on ClinicalTrials.gov |
What this research studies
Malaria continues to be a major health challenge worldwide, and the parasites that cause it are constantly becoming resistant to existing drugs. This means we urgently need new ways to treat the disease. Our team is searching through a large collection of chemical compounds to find promising new candidates that can effectively kill the malaria parasite. We are carefully selecting compounds that are potent against the parasite, safe for human cells, and have good properties for becoming a medicine.
Who could benefit from this research
Good fit: Patients who suffer from malaria, particularly young African children, are the ultimate beneficiaries of this research.
Not a fit: Healthy individuals or those without malaria would not directly benefit from this specific drug discovery effort.
Why it matters
Potential benefit: If successful, this work could lead to the development of new, effective drugs to treat malaria, especially important as current treatments face increasing resistance.
How similar studies have performed: This project seeks novel chemical starting points, building on the ongoing need for new anti-malarial drugs due to widespread resistance to existing treatments.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PHILLIPS, MARGARET A. — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: PHILLIPS, MARGARET A.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.