Finding New Medicines for Healing and Cell Protection
Methods and approaches to expand the pharmacological toolset
['FUNDING_OTHER'] · SCRIPPS RESEARCH INSTITUTE, THE · NIH-11123113
This project aims to discover new small molecules that can help the body heal and protect cells from stress, potentially leading to new treatments for various conditions.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SCRIPPS RESEARCH INSTITUTE, THE (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11123113 on ClinicalTrials.gov |
What this research studies
Our laboratory is working to identify tiny molecules that can influence how our bodies work, with the goal of creating new medicines. We are focusing on two main areas: first, developing tools to help tissues repair themselves, particularly by targeting pathways involved in regeneration and stem cell activity. Second, we are exploring ways to activate the body's natural defenses against cellular stress, like heat or oxidative damage, by finding new molecules that can turn on protective responses. This work involves understanding the intricate signals within cells to find new ways to promote healing and protect against disease.
Who could benefit from this research
Good fit: Patients with conditions requiring tissue repair or those affected by diseases linked to cellular stress responses may ultimately benefit from future treatments developed from this research.
Not a fit: Patients whose conditions are not related to tissue regeneration or cellular stress pathways are unlikely to directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to the development of entirely new drugs for regenerative medicine and conditions caused by cellular stress.
How similar studies have performed: Our team has already developed superior activators for certain protective pathways in animal models compared to existing clinical-stage molecules, indicating promise for these approaches.
Where this research is happening
LA JOLLA, UNITED STATES
- SCRIPPS RESEARCH INSTITUTE, THE — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BOLLONG, MICHAEL J — SCRIPPS RESEARCH INSTITUTE, THE
- Study coordinator: BOLLONG, MICHAEL J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.