Finding new genetic targets for Alzheimer's disease treatment and prevention.
Therapeutic target discovery in ADSP data via comprehensive whole-genome analysis incorporating ethnic diversity and systems approaches
This study is looking for new genetic clues that might help us understand why some people get Alzheimer's disease and others don't, especially in different ethnic groups, so we can find better ways to treat and prevent it.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10683597 on NIH RePORTER |
What this research studies
This research focuses on discovering new genetic variants that may increase the risk of Alzheimer's disease or provide protection against it, particularly in diverse ethnic populations. By analyzing whole genome and whole exome sequencing data, the project aims to identify novel pathways that could lead to effective treatments and preventive measures for Alzheimer's disease. Patients may benefit from this research as it seeks to enhance understanding of the genetic factors involved in Alzheimer's, potentially leading to personalized treatment options.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals from diverse ethnic backgrounds who are at risk for or affected by Alzheimer's disease.
Not a fit: Patients who do not have a genetic predisposition to Alzheimer's disease or are not from the targeted ethnic groups may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment strategies and preventive measures for Alzheimer's disease.
How similar studies have performed: Previous research has shown success in identifying genetic factors associated with Alzheimer's disease, suggesting that this approach has the potential for meaningful discoveries.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Destefano, Anita L — Boston University Medical Campus
- Study coordinator: Destefano, Anita L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.