Finding new genetic targets for Alzheimer's disease treatment and prevention.
Therapeutic target discovery in ADSP data via comprehensive whole-genome analysis incorporating ethnic diversity and systems approaches
This study is looking at how our genes might affect the risk of Alzheimer's disease, especially in different ethnic groups, to find new ways to treat and prevent it, and it could help patients understand more about the condition.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10474531 on NIH RePORTER |
What this research studies
This research investigates genetic factors that contribute to Alzheimer's disease risk and protection, focusing on diverse ethnic populations. By analyzing whole genome and whole exome sequencing data, the study aims to identify new genomic variants and pathways that could lead to better treatment and prevention strategies. Patients may benefit from the insights gained through this research, which seeks to enhance understanding of Alzheimer's disease at a genetic level. The research team includes experts in bioinformatics, statistics, and clinical aspects of Alzheimer's, ensuring a comprehensive approach to the investigation.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals from diverse ethnic backgrounds who are at risk for or affected by Alzheimer's disease.
Not a fit: Patients who do not have a genetic predisposition to Alzheimer's disease or who are not from the targeted ethnic groups may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments and preventive measures for Alzheimer's disease.
How similar studies have performed: Previous research has shown success in identifying genetic variants related to Alzheimer's disease, suggesting that this approach has the potential for meaningful discoveries.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Destefano, Anita L — Boston University Medical Campus
- Study coordinator: Destefano, Anita L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.