Finding new genes that affect bone health
Discovery of osteoblast and osteoclast bone mass effector genes using advanced genomics
This study is looking at the genes that might cause osteoporosis, a condition that makes bones weak, to help find new ways to prevent and treat it for people who are affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11078194 on NIH RePORTER |
What this research studies
This research investigates the genetic factors that contribute to osteoporosis, a condition that weakens bones and affects millions of people. By using advanced genomic techniques, the researchers aim to identify new genes involved in the balance of bone formation and resorption. The study employs a multi-step computational approach that integrates various genomic data to pinpoint these genes, which could lead to better understanding and treatment of osteoporosis. Patients may benefit from the eventual development of new therapies aimed at preventing and treating this debilitating disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals, particularly children under 11 years old, who may be at risk for osteoporosis or related bone health issues.
Not a fit: Patients who are already diagnosed with osteoporosis and are older than 11 years may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve bone health and prevent osteoporosis.
How similar studies have performed: Previous research has successfully identified genetic factors related to osteoporosis, suggesting that this approach has the potential for meaningful discoveries.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Hankenson, Kurt David — University of Michigan at Ann Arbor
- Study coordinator: Hankenson, Kurt David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.