Finding new drugs to treat a fungal infection called coccidioidomycosis
Screening Repurposing Libraries for the Identification of Drugs with Novel anti-Coccidioidal Activity
This study is looking for new and better medicines to help people with coccidioidomycosis, a fungal infection, by testing existing drugs to see how well they can stop the fungus from growing.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas San Antonio NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-11004656 on NIH RePORTER |
What this research studies
This research focuses on coccidioidomycosis, a fungal infection caused by Coccidioides posadasii and Coccidioides immitis, which affects approximately 150,000 people in the U.S. each year. The study aims to identify new therapeutic drugs by screening existing drug libraries for their effectiveness against the parasitic form of the fungus. Researchers will utilize a novel methodology called fungal cytological profiling (FCP) to assess how these drugs affect the growth and development of the fungus. This approach is designed to find safer and more effective treatments for patients suffering from this infection.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with coccidioidomycosis or those at high risk of infection.
Not a fit: Patients with non-fungal infections or those who do not have coccidioidomycosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of safer and more effective treatments for coccidioidomycosis.
How similar studies have performed: Previous research has shown promise in repurposing existing drugs for fungal infections, indicating potential success for this approach.
Where this research is happening
San Antonio, United States
- University of Texas San Antonio — San Antonio, United States (Active)
Researchers
- Principal investigator: Yu, Jieh-Juen — University of Texas San Antonio
- Study coordinator: Yu, Jieh-Juen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.