Finding new drugs to stop the spread of treatment-resistant brain cancer cells.

High-throughput Identification and Validation of Drugs to Target Migrating and Treatment-Resistant Glioblastoma Cells

NIH-funded research University of Texas Arlington · NIH-11043851

This study is looking for new ways to stop the spread of glioblastoma, a tough type of brain cancer, by testing new drugs that could help make treatment more effective and improve survival for patients.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Arlington NIH-funded
Lab location1 site (Arlington, United States)
Project IDNIH-11043851 on NIH RePORTER

What this research studies

This research focuses on glioblastoma, a type of brain cancer known for its aggressive spread into surrounding brain tissue. Current treatments have limited effectiveness, leading to poor survival rates. The research team is developing advanced methods to identify and validate new drugs that can effectively block the migration of these cancer cells. By using innovative high-throughput screening techniques, they aim to create a more effective treatment strategy that could transform glioblastoma into a more manageable condition.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients diagnosed with glioblastoma, particularly those whose tumors are resistant to current treatments.

Not a fit: Patients with non-cancerous brain conditions or those with glioblastoma that has not spread may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapies that significantly improve survival rates and quality of life for patients with glioblastoma.

How similar studies have performed: Previous research has shown promise in targeting cancer cell migration, indicating that this approach could lead to significant advancements in glioblastoma treatment.

Where this research is happening

Arlington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Anti-Cancer Agentsanti-cancer druganti-cancer researchanti-cancer therapy
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.