Finding new causes of ovarian cancer from non-coding DNA
Identifying new drivers of ovarian cancer from the non-coding genome by converging germline risk variants and somatic mutations
This study is looking at how certain genetic changes in DNA might play a role in ovarian cancer, with the hope of finding new ways to prevent and treat the disease, and it's for anyone affected by ovarian cancer who wants to learn more about their condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cedars-Sinai Medical Center NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10871895 on NIH RePORTER |
What this research studies
This research investigates how specific genetic variations in the non-coding regions of DNA may contribute to ovarian cancer. By analyzing both inherited risk factors and mutations that occur in tumors, the study aims to uncover new biological mechanisms that drive the disease. Patients may benefit from insights gained through advanced computational models and next-generation sequencing technologies, which could lead to improved prevention and treatment strategies. The research is conducted at Cedars-Sinai Medical Center, a leading institution in cancer biology.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of ovarian cancer or those diagnosed with the disease.
Not a fit: Patients with non-genetic forms of ovarian cancer or those without a family history may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potentially new treatments for ovarian cancer.
How similar studies have performed: Other research has shown promise in identifying genetic factors in cancer, suggesting that this approach could yield valuable insights.
Where this research is happening
Los Angeles, United States
- Cedars-Sinai Medical Center — Los Angeles, United States (Active)
Researchers
- Principal investigator: Peng, Pei-Chen — Cedars-Sinai Medical Center
- Study coordinator: Peng, Pei-Chen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.