Finding new blood markers for early detection of sepsis
Discovery and Characterization of Novel Sepsis Proteome Biomarkers
['FUNDING_R01'] · OKLAHOMA MEDICAL RESEARCH FOUNDATION · NIH-10908533
This study is looking for new ways to spot sepsis early by examining blood samples from both monkeys and people, hoping to find specific proteins that could help create better blood tests for quicker diagnosis and treatment.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OKLAHOMA MEDICAL RESEARCH FOUNDATION (nih funded) |
| Locations | 1 site (OKLAHOMA CITY, UNITED STATES) |
| Trial ID | NIH-10908533 on ClinicalTrials.gov |
What this research studies
This research focuses on discovering and validating new biomarkers for sepsis using advanced mass spectrometry-based proteomics. By analyzing blood samples from both non-human primates and clinical patients, the study aims to identify specific proteins that can serve as early diagnostic tools for sepsis. The approach combines unbiased proteomics with bioinformatics to ensure a comprehensive evaluation of potential biomarkers. If successful, these findings could lead to the development of new blood tests that improve early detection and treatment of sepsis.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for sepsis, such as those with underlying conditions like cancer, diabetes, or cardiovascular diseases.
Not a fit: Patients who are not at risk for sepsis or do not have any underlying health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and better treatment options for patients with sepsis.
How similar studies have performed: Previous research has shown promise in using proteomics for biomarker discovery, indicating that this approach could yield significant results.
Where this research is happening
OKLAHOMA CITY, UNITED STATES
- OKLAHOMA MEDICAL RESEARCH FOUNDATION — OKLAHOMA CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LUPU, FLOREA — OKLAHOMA MEDICAL RESEARCH FOUNDATION
- Study coordinator: LUPU, FLOREA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.