Finding new blood markers for Adrenomyeloneuropathy
Discovery and validation of multi-omic plasma biomarkers for Adrenomyeloneuropathy
['FUNDING_OTHER'] · HUGO W. MOSER RES INST KENNEDY KRIEGER · NIH-11143890
This project aims to find new markers in blood samples that can help predict and track the progression of Adrenomyeloneuropathy (AMN), a serious neurological condition.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | HUGO W. MOSER RES INST KENNEDY KRIEGER (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11143890 on ClinicalTrials.gov |
What this research studies
We are looking for new ways to understand how Adrenomyeloneuropathy (AMN) progresses by examining blood samples from patients. Our team will use advanced 'omics' techniques, which look at many different biological molecules, along with machine learning to find specific patterns. These patterns could become new biomarkers, which are like early warning signs or progress indicators for the disease. The goal is to identify markers that can show how severe the disease is and predict future changes, helping us better understand and manage AMN.
Who could benefit from this research
Good fit: This research is focused on individuals diagnosed with Adrenomyeloneuropathy (AMN) who may be asked to provide blood plasma samples.
Not a fit: Patients without Adrenomyeloneuropathy or those not able to provide blood samples may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new blood tests that help doctors predict how Adrenomyeloneuropathy will progress and monitor the effectiveness of future treatments.
How similar studies have performed: This project builds on prior research using cutting-edge 'omics' techniques, but the specific combination of markers and machine learning for AMN progression is a novel approach.
Where this research is happening
BALTIMORE, UNITED STATES
- HUGO W. MOSER RES INST KENNEDY KRIEGER — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FATEMI, S. ALI — HUGO W. MOSER RES INST KENNEDY KRIEGER
- Study coordinator: FATEMI, S. ALI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Addison disease-cerebral sclerosis syndrome, Addison disease-spastic paraplegia syndrome, Addison-Schilder syndrome, Alzheimer disease dementia, Alzheimer syndrome