Finding new antiviral treatments for Mpox virus
Official title: Discovery of Antivirals Targeting Mpox Virus
Funded at Emory University · NIH-11086110 · Data updated 2026-11-12
This study is looking for new antiviral medicines to help fight the Mpox virus, which is becoming a big health concern, and it's for anyone who wants to know more about potential treatments since there aren't any approved drugs for it yet.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | May 8, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $767,057 |
| NIH project number | 5R01AI177696-02 |
| Project ID | NIH-11086110 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who are at risk of or have been diagnosed with Mpox virus infections.
✕Less likely to help
Patients who are not at risk for Mpox or have not been diagnosed with the virus may not benefit from this research.
What this research studies
This research aims to discover effective antiviral medications specifically targeting the Mpox virus, which has recently emerged as a significant public health threat. The team will explore various compounds and their effectiveness against the virus, utilizing advanced laboratory techniques to assess their potential. By focusing on the mechanisms of the virus and how it interacts with human cells, the research seeks to identify new treatment options that could be used to combat Mpox infections. This work is crucial as there are currently no FDA-approved drugs for treating Mpox.
Why it matters
Potential benefit: If successful, this research could lead to the development of new antiviral drugs that effectively treat Mpox virus infections.
How similar studies have gone: While there have been efforts to develop antiviral treatments for related viruses, this specific approach to targeting Mpox is relatively novel and untested.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Sarafianos, Stefan G — Emory University
- Study coordinator: Sarafianos, Stefan G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.