Finding new antifungal treatments for Valley Fever
Official title: Repurposing Drugs to Discover Novel Antifungals for Coccidioidomycosis
Funded at University of Texas San Antonio · NIH-10998785 · Data updated 2026-11-12
This study is looking for new ways to treat Valley Fever by testing existing medications to see if they can work better together, aiming to help people who are struggling with this illness.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas San Antonio NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $37,513 |
| NIH project number | 1F31AI186506-01 |
| Project ID | NIH-10998785 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with coccidioidomycosis or those at high risk of infection due to environmental exposure.
✕Less likely to help
Patients with non-fungal respiratory infections or those who do not reside in endemic areas may not benefit from this research.
What this research studies
This research focuses on discovering new antifungal medications for coccidioidomycosis, commonly known as Valley Fever, which is caused by the Coccidioides fungus. The project aims to repurpose existing FDA-approved drugs to create effective treatments against this disease, which can lead to severe health complications. Researchers have already screened thousands of compounds and identified several promising candidates that could enhance current treatment options. By testing these candidates in combination with existing antifungals, the study seeks to improve patient outcomes and combat drug resistance.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer treatments for patients suffering from Valley Fever.
How similar studies have gone: Other research has shown promise in repurposing existing drugs for fungal infections, indicating that this approach could be effective.
Where this research is happening
-
University of Texas San Antonio
San Antonio, United States Active
Researchers
- Principal investigator: Saeger, Sarah Beth — University of Texas San Antonio
- Study coordinator: Saeger, Sarah Beth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.