Finding new antifungal treatments for Valley Fever
Repurposing Drugs to Discover Novel Antifungals for Coccidioidomycosis
This study is looking for new ways to treat Valley Fever by testing existing medications to see if they can work better together, aiming to help people who are struggling with this illness.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas San Antonio NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-10998785 on NIH RePORTER |
What this research studies
This research focuses on discovering new antifungal medications for coccidioidomycosis, commonly known as Valley Fever, which is caused by the Coccidioides fungus. The project aims to repurpose existing FDA-approved drugs to create effective treatments against this disease, which can lead to severe health complications. Researchers have already screened thousands of compounds and identified several promising candidates that could enhance current treatment options. By testing these candidates in combination with existing antifungals, the study seeks to improve patient outcomes and combat drug resistance.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with coccidioidomycosis or those at high risk of infection due to environmental exposure.
Not a fit: Patients with non-fungal respiratory infections or those who do not reside in endemic areas may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer treatments for patients suffering from Valley Fever.
How similar studies have performed: Other research has shown promise in repurposing existing drugs for fungal infections, indicating that this approach could be effective.
Where this research is happening
San Antonio, United States
- University of Texas San Antonio — San Antonio, United States (Active)
Researchers
- Principal investigator: Saeger, Sarah Beth — University of Texas San Antonio
- Study coordinator: Saeger, Sarah Beth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.