Finding new anticancer agents from bacterial natural products
Official title: Discovery and characterization of synthetic bioinformatic natural product anticancer agents
Funded at Rockefeller University · NIH-11081664 · Data updated 2026-11-12
This study is looking for new cancer-fighting medicines made from natural substances found in bacteria, hoping to find unique treatments that could help patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rockefeller University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | May 1, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $423,140 |
| NIH project number | 5R01CA280019-03 |
| Project ID | NIH-11081664 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with cancer who are seeking new treatment options.
✕Less likely to help
Patients with non-cancerous conditions or those who have exhausted all treatment options may not benefit from this research.
What this research studies
This research focuses on discovering and characterizing new anticancer agents derived from bacterial natural products. By utilizing advanced bioinformatics and genomic analyses, the team aims to unlock previously inaccessible metabolites encoded by the global microbiome. This approach seeks to identify unique compounds that could serve as effective treatments for cancer, moving beyond traditional methods that often overlook the vast potential of microbial diversity. Patients may benefit from innovative therapies that arise from these novel compounds.
Why it matters
Potential benefit: If successful, this research could lead to the development of new and effective anticancer therapies.
How similar studies have gone: Other research has shown promise in utilizing bacterial natural products for drug development, indicating a strong potential for success in this area.
Where this research is happening
-
Rockefeller University
New York, United States Active
Researchers
- Principal investigator: Brady, Sean F — Rockefeller University
- Study coordinator: Brady, Sean F
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.