Finding new antibiotics to fight resistant bacteria
Discovering antimicrobials acting against MDR pathogens
This study is looking for new antibiotics to help fight tough infections caused by bacteria that don't respond to regular treatments, especially for people dealing with multi-drug resistant infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northeastern University NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10901856 on NIH RePORTER |
What this research studies
This research aims to tackle the growing problem of antimicrobial resistance by discovering new antibiotics that can effectively combat multi-drug resistant (MDR) pathogens, particularly focusing on bacteria like Acinetobacter baumannii and others. The researchers are developing innovative methods to explore a wider range of bacterial species, especially those that are not easily cultured in laboratories. By screening these uncultured bacteria, they hope to identify novel compounds that can serve as effective treatments against resistant infections. This approach builds on past successes in antibiotic discovery while addressing the limitations of current methods.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients suffering from infections caused by multi-drug resistant bacteria.
Not a fit: Patients with infections caused by non-bacterial pathogens or those that are not resistant to current antibiotics may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new antibiotics that effectively treat infections caused by resistant bacteria, improving patient outcomes.
How similar studies have performed: Previous research has successfully identified novel antibiotics through similar innovative approaches, indicating potential for success in this area.
Where this research is happening
Boston, United States
- Northeastern University — Boston, United States (Active)
Researchers
- Principal investigator: Lewis, Kim — Northeastern University
- Study coordinator: Lewis, Kim
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.