Finding new antibiotics from soil bacteria that fight drug-resistant infections
Isolation, identification and characterization of potentially novel antibiotics from rhizospheric bacteria without detectable in vitro resistance
This study is looking for new antibiotics made by soil bacteria that can help treat infections caused by germs that don’t respond to current medicines, so patients can have better options for their health.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rochester Institute of Technology NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10581945 on NIH RePORTER |
What this research studies
This research focuses on discovering and characterizing new antibiotics produced by bacteria found in soil, specifically targeting those that do not show resistance to existing antibiotics. The researchers will isolate these bacteria and analyze their genetic makeup to identify the specific gene clusters responsible for antibiotic production. By understanding these pathways, the goal is to develop effective treatments against multi-drug resistant infections, which are a growing global health concern. Patients may benefit from new antibiotic options that can effectively treat infections caused by resistant bacteria.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from infections caused by multi-drug resistant bacteria.
Not a fit: Patients with infections caused by bacteria that are not resistant to current antibiotics may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of novel antibiotics that effectively treat infections caused by drug-resistant bacteria.
How similar studies have performed: Other research has shown promise in discovering new antibiotics from natural sources, indicating that this approach could yield significant results.
Where this research is happening
Rochester, United States
- Rochester Institute of Technology — Rochester, United States (Active)
Researchers
- Principal investigator: Hudson, Andre O — Rochester Institute of Technology
- Study coordinator: Hudson, Andre O
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.