Finding new antibiotics from fungi
Official title: Discovering novel natural products from fungal species
Funded at Chemia Biosciences, INC. · NIH-10920019 · Data updated 2026-11-12
This study is looking for new natural antibiotics from fungi to help fight infections that don't respond to regular treatments, and it's for anyone concerned about antibiotic resistance.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Chemia Biosciences, INC. NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $308,925 |
| NIH project number | 1R43GM154504-01 |
| Project ID | NIH-10920019 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from infections that are difficult to treat due to antibiotic resistance.
✕Less likely to help
Patients with infections that are already effectively treated by existing antibiotics may not benefit from this research.
What this research studies
This research focuses on discovering novel natural products from fungal species to combat antibiotic resistance, a growing public health crisis. By utilizing advanced technologies like high-throughput mass spectrometry and genome mining, the team aims to identify new antibiotics that can effectively target resistant pathogens. The approach involves analyzing microbial cultures to predict the molecular products of biosynthetic gene clusters, which are responsible for producing natural antibiotics. This innovative methodology seeks to overcome the limitations of traditional antibiotic discovery techniques.
Why it matters
Potential benefit: If successful, this research could lead to the development of new antibiotics that effectively treat infections caused by antibiotic-resistant bacteria.
How similar studies have gone: Other research has shown promise in discovering new antibiotics through innovative techniques, indicating that this approach could yield significant results.
Where this research is happening
-
Chemia Biosciences, INC.
Pittsburgh, United States Active
Researchers
- Principal investigator: Behsaz, Bahar — Chemia Biosciences, INC.
- Study coordinator: Behsaz, Bahar
Related research
Other NIH-funded projects on the same topics.
-
Discovering new natural products from fungi for better medicines
A funding-supported project uses computer and lab tools to find new antimicrobial compounds made by fungi that could become the antibiotics of tomorrow.
-
A new platform to discover natural product molecules
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-
Finding new natural antibiotics to fight resistant infections
This study is looking for new natural antibiotics to help fight infections that are becoming harder to treat because of antibiotic resistance, and it's for anyone who might be affected by these tough-to-treat infections.
-
Finding new small molecule drugs using advanced database techniques
This study is looking for new natural medicines by using advanced technology to explore plants and microbes, hoping to find fresh treatments that could help people with various health conditions.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.