Finding markers in the blood to predict cognitive decline in Parkinson's disease.

Who could benefit from this research

What this research studies

This research aims to identify specific metabolomic markers in the blood and cerebrospinal fluid of patients with Parkinson's disease (PD) to predict the onset of cognitive impairment. By utilizing advanced techniques like gas chromatography mass-spectroscopy (GC-MS) and liquid chromatography-mass spectroscopy (LC-MS), the study will analyze samples from patients who have been monitored over time. The goal is to establish a clear link between metabolomic profiles and the transition from normal cognition to cognitive impairment, which could inform treatment strategies and clinical trial designs.

Why it matters

Where this research is happening

• University of Kentucky
  Lexington, United States Active

Researchers

• Principal investigator: Yamasaki, Tritia — University of Kentucky
• Study coordinator: Yamasaki, Tritia

Related research

Other NIH-funded projects on the same topics.

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.