Finding genetic factors linked to non-alcoholic fatty liver disease
Identification and Characterization of Loci Associated with Non-alcoholic Fatty Liver Disease
['FUNDING_R01'] · WAKE FOREST UNIVERSITY HEALTH SCIENCES · NIH-10804669
This study is looking at how certain genes might affect the risk of developing non-alcoholic fatty liver disease (NAFLD) to help improve diagnosis and treatment for people with this condition, especially those from groups that haven't been studied much before.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WAKE FOREST UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (WINSTON-SALEM, UNITED STATES) |
| Trial ID | NIH-10804669 on ClinicalTrials.gov |
What this research studies
This research aims to identify genetic variations that contribute to non-alcoholic fatty liver disease (NAFLD), a condition where excess fat accumulates in the liver. By analyzing the genomes of a diverse group of individuals, the study seeks to uncover rare genetic variants that may influence the risk of developing NAFLD. The research will utilize whole genome sequencing to explore these genetic factors, particularly focusing on populations that have been underrepresented in previous studies. The ultimate goal is to enhance understanding of NAFLD and improve diagnosis and treatment options for affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals from diverse ethnic backgrounds who are at risk for or diagnosed with non-alcoholic fatty liver disease.
Not a fit: Patients with liver disease caused by alcohol consumption or other non-genetic factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for non-alcoholic fatty liver disease.
How similar studies have performed: Previous research has successfully identified genetic factors associated with liver disease, suggesting that this approach may yield valuable insights.
Where this research is happening
WINSTON-SALEM, UNITED STATES
- WAKE FOREST UNIVERSITY HEALTH SCIENCES — WINSTON-SALEM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ALLRED, NICHOLETTE D. — WAKE FOREST UNIVERSITY HEALTH SCIENCES
- Study coordinator: ALLRED, NICHOLETTE D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.