Finding Early Signs of Diabetic Eye Damage

Dynamic Tracer Kinetic Model to Detect Preclinical Diabetic Retinopathy (DR)

NIH-funded research The Trustees of the Stevens Institute of Technology · NIH-11091494

This project is developing a new way to find early signs of eye damage from diabetes, even before vision problems start.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionThe Trustees of the Stevens Institute of Technology NIH-funded
Lab location1 site (Hoboken, United States)
Project IDNIH-11091494 on NIH RePORTER

What this research studies

Diabetic retinopathy (DR) can cause severe vision loss, but it often develops silently for years before symptoms appear. Catching these early changes is crucial for preventing vision problems, but current methods aren't always sensitive enough or easy to use in a regular clinic. This project aims to create a more effective imaging technique to spot subtle changes in blood vessels in the eye that signal early DR. By improving how we see and measure these tiny changes, we hope to give doctors a better tool for early detection.

Who could benefit from this research

Good fit: People with diabetes, especially those in the early stages or at risk of developing diabetic retinopathy, would be ideal candidates for future applications of this technology.

Not a fit: Patients who already have advanced diabetic retinopathy or significant vision loss may not directly benefit from this early detection method.

Why it matters

Potential benefit: If successful, this new imaging method could help doctors identify diabetic retinopathy much earlier, allowing for timely interventions to prevent vision loss.

How similar studies have performed: While other imaging technologies have shown promise in visualizing retinal vessels, this project seeks to enhance detection sensitivity and quantification beyond current limitations.

Where this research is happening

Hoboken, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.