Finding early signs of Alzheimer's disease using special probes
Identifying biomarkers for the early detection of Alzheimer's disease using phage display
['FUNDING_R15'] · UNIVERSITY OF WEST FLORIDA · NIH-10974577
This study is working on a new blood or spinal fluid test to spot early signs of Alzheimer's disease by looking for specific changes in a protein called tau, which could help doctors diagnose and track the disease better.
Quick facts
| Phase | ['FUNDING_R15'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WEST FLORIDA (nih funded) |
| Locations | 1 site (PENSACOLA, UNITED STATES) |
| Trial ID | NIH-10974577 on ClinicalTrials.gov |
What this research studies
This research aims to develop a new screening test that can detect early biochemical changes related to Alzheimer's disease (AD) by analyzing blood or cerebrospinal fluid (CSF). The focus is on identifying specific protein modifications associated with AD, particularly those related to the tau protein. By using phage display technology, the researchers hope to create highly sensitive probes that can accurately identify these changes, leading to better diagnosis and monitoring of the disease. The study will validate its findings in a larger group of participants to ensure its effectiveness.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for Alzheimer's disease or those experiencing early symptoms of cognitive decline.
Not a fit: Patients with advanced Alzheimer's disease or those without any cognitive symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of Alzheimer's disease, allowing for timely interventions.
How similar studies have performed: Previous research has shown promise in using similar biomarker approaches for Alzheimer's detection, indicating potential for success in this study.
Where this research is happening
PENSACOLA, UNITED STATES
- UNIVERSITY OF WEST FLORIDA — PENSACOLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GUTTMANN, RODNEY P — UNIVERSITY OF WEST FLORIDA
- Study coordinator: GUTTMANN, RODNEY P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer disease detection, Alzheimer syndrome, Alzheimer's Disease