Finding early signs of Alzheimer's disease using brain imaging

Identification of early markers for Alzheimer's disease by neuroimaging

NIH-funded research Yale University · NIH-11052998

This study is looking at how changes in the parts of the brain that control smell and memory might help spot early signs of Alzheimer's disease, so if you're interested in understanding more about your brain health, this research could be for you!

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11052998 on NIH RePORTER

What this research studies

This research investigates how changes in the brain's olfactory and memory circuits can serve as early indicators of Alzheimer's disease (AD). By using advanced neuroimaging techniques, the study aims to identify structural and functional alterations in specific brain regions associated with smell and memory long before clinical symptoms appear. Patients may undergo imaging tests to assess their brain function and structure, helping to uncover potential biomarkers for early AD detection.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who are at risk for Alzheimer's disease or those experiencing early signs of cognitive decline.

Not a fit: Patients with advanced Alzheimer's disease or those who do not exhibit any cognitive decline may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier diagnosis and intervention for Alzheimer's disease, potentially slowing its progression.

How similar studies have performed: Previous research has shown promise in identifying early biomarkers for Alzheimer's disease using neuroimaging techniques, suggesting that this approach could be effective.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer disease detectionAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.