Finding early signs of Alzheimer's disease using brain imaging
Official title: Identification of early markers for Alzheimer's disease by neuroimaging
Funded at Yale University · NIH-11052998 · Data updated 2026-11-12
This study is looking at how changes in the parts of the brain that control smell and memory might help spot early signs of Alzheimer's disease, so if you're interested in understanding more about your brain health, this research could be for you!
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 30, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $460,548 |
| NIH project number | 1R21AG091590-01 |
| Project ID | NIH-11052998 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who are at risk for Alzheimer's disease or those experiencing early signs of cognitive decline.
✕Less likely to help
Patients with advanced Alzheimer's disease or those who do not exhibit any cognitive decline may not benefit from this research.
What this research studies
This research investigates how changes in the brain's olfactory and memory circuits can serve as early indicators of Alzheimer's disease (AD). By using advanced neuroimaging techniques, the study aims to identify structural and functional alterations in specific brain regions associated with smell and memory long before clinical symptoms appear. Patients may undergo imaging tests to assess their brain function and structure, helping to uncover potential biomarkers for early AD detection.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and intervention for Alzheimer's disease, potentially slowing its progression.
How similar studies have gone: Previous research has shown promise in identifying early biomarkers for Alzheimer's disease using neuroimaging techniques, suggesting that this approach could be effective.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Ganganna, Basavaraju Sanganahalli — Yale University
- Study coordinator: Ganganna, Basavaraju Sanganahalli
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.