Finding early protein markers for Alzheimer's disease and cognitive decline
Integrated multi-omics approach to identify early protein biomarkers in Alzheimer's disease and cognitive decline
This study is looking for early signs in blood proteins that could help spot Alzheimer's disease and memory problems sooner, which could lead to better ways to diagnose and treat the condition.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11021067 on NIH RePORTER |
What this research studies
This research aims to identify early protein biomarkers that can indicate the onset of Alzheimer's disease (AD) and cognitive decline. By utilizing advanced technology to analyze plasma proteins from a large cohort, the study seeks to uncover associations between these proteins and the progression of AD. The research will leverage existing data from a significant population-based study, which includes genetic information and cognitive assessments, to enhance understanding of AD and improve prevention strategies. Patients may benefit from the identification of biomarkers that could lead to earlier diagnosis and targeted treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for Alzheimer's disease, particularly those with a family history or early signs of cognitive decline.
Not a fit: Patients who are already diagnosed with advanced Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and better management of Alzheimer's disease, ultimately improving patient outcomes.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for Alzheimer's disease, suggesting that this approach could yield valuable insights.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Fohner, Alison Elizabeth — University of Washington
- Study coordinator: Fohner, Alison Elizabeth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.