Finding early blood markers for age-related vision loss
Pre-diagnosis Biomarker Discovery for Age-Related Macular Degeneration
This study is looking for clues in the blood that could help spot age-related macular degeneration (AMD) before it starts, so healthy people can get help sooner if they’re at risk.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11000802 on NIH RePORTER |
What this research studies
This research aims to discover blood-based biomarkers that can predict the onset of age-related macular degeneration (AMD) in healthy individuals. By analyzing plasma samples from donors who later developed AMD and comparing them to those who did not, the study will utilize advanced techniques to identify differences in protein composition and optical properties. The research will also incorporate genetic information to enhance the understanding of these biomarkers. This could lead to earlier detection and intervention strategies for AMD.
Who could benefit from this research
Good fit: Ideal candidates for this research are healthy individuals over the age of 50 who are at risk for developing age-related macular degeneration.
Not a fit: Patients who are already diagnosed with age-related macular degeneration may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enable earlier diagnosis and preventive measures for age-related macular degeneration, potentially preserving vision for many individuals.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for various diseases, suggesting that this approach could yield valuable insights for AMD as well.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Blenkinsop, Timothy a. — Icahn School of Medicine at Mount Sinai
- Study coordinator: Blenkinsop, Timothy a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.