Finding clearer types and causes of adult-onset diabetes using medical records
Improving disease subtyping and physiological characterization of adult-onset diabetes in electronic health records
Using medical records and genetic and molecular data to identify different forms of adult-onset diabetes so care can be more tailored for adults.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11172528 on NIH RePORTER |
What this research studies
Researchers will use large-scale electronic health records (EHRs) from academic medical centers to group adults with diabetes by shared clinical features and how they respond to treatments. The team will combine EHR information with multi-omics data (for example, genetic and molecular profiles) to better understand the biological drivers behind each diabetes subtype. A special focus is placed on people of diverse ancestries, including detailed molecular studies in African American participants. The goal is to create a framework that links disease patterns in the medical record to underlying physiology and treatment needs.
Who could benefit from this research
Good fit: Adults (21 years and older) with adult-onset diabetes whose medical records and, in some parts of the project, biological samples or genetic data can be shared for research.
Not a fit: People without adult-onset diabetes, children, or adults who cannot share EHR data or biological samples are unlikely to be eligible or directly benefit from participation.
Why it matters
Potential benefit: If successful, this work could help doctors choose medications and prevention strategies that better match a person’s type of diabetes and risk of complications.
How similar studies have performed: Previous research has identified meaningful diabetes subgroups using clinical data, but combining very large EHR datasets with multi-omics—especially focused on African American populations—is relatively new.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Ng, Maggie — Vanderbilt University Medical Center
- Study coordinator: Ng, Maggie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.