NIH-funded research U01 cooperative agreement

Finding blood markers that show how aging affects heart health

Official title: Identifying Organ-Specific Blood Biomarkers of Aging and Assessing their Effects on Cardiovascular Health

Funded at Buck Institute for Research on Aging · NIH-11115652 · Data updated 2026-11-12

This study is looking at how getting older affects heart health by checking certain blood markers and how different organs age together, so we can better understand heart problems and find ways to help.

More Aging research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionBuck Institute for Research on Aging
NIH-funded
Lab location1 site (Novato, United States)
Project startJune 15, 2024
Project endMarch 31, 2029
Funding year2025
Award (this year)$703,365
NIH project number5U01AG086214-02
Project IDNIH-11115652 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults who may be experiencing age-related cardiovascular issues.

Less likely to help

Patients who are younger and do not have any signs of cardiovascular dysfunction may not benefit from this research.

What this research studies

This research investigates how aging impacts the health of the heart by identifying specific blood biomarkers linked to organ aging. It utilizes advanced data analysis techniques, including deep learning, to study large groups of individuals over time. By examining the interactions between different organs and their aging processes, the research aims to uncover how these factors contribute to heart dysfunction. The goal is to develop a better understanding of how aging affects cardiovascular health and to identify potential interventions.

Why it matters

Potential benefit: If successful, this research could lead to new ways to monitor and improve heart health in aging individuals.

How similar studies have gone: Previous research has shown promise in using biomarkers to understand aging and its effects on health, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Buck Institute for Research on Aging
    Novato, United States
    Active

Researchers

  • Principal investigator: Furman, David — Buck Institute for Research on Aging
  • Study coordinator: Furman, David

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.