Finding blood markers and causes of alcohol-related acute pancreatitis
Biomarkers and pathogenesis of Alcoholic acute pancreatitis
This project looks for blood markers that could help doctors identify when pancreatitis is caused by alcohol and predict how severe it will be for people admitted with acute pancreatitis.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Arizona NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project ID | NIH-11243487 on NIH RePORTER |
What this research studies
If you join, researchers will collect blood samples from people hospitalized with acute pancreatitis to measure chemicals called FAEEs and PEth. They will compare marker levels in people thought to have alcohol-related pancreatitis versus other causes and will relate levels to how sick people become. The team will also look at how fat breakdown in the belly might release FAEEs that make the illness worse. Results come from patient samples and clinical records at the hospital.
Who could benefit from this research
Good fit: Adults hospitalized with acute pancreatitis, especially when alcohol may be the cause, who can provide blood samples and medical history are the ideal candidates.
Not a fit: People whose pancreatitis is clearly due to non-alcohol causes or who cannot provide blood samples or clinical information may not benefit directly from this project.
Why it matters
Potential benefit: If successful, this work could let doctors more reliably detect alcohol-related pancreatitis and identify patients at risk for severe illness sooner.
How similar studies have performed: Prior smaller studies and laboratory data suggest FAEEs and PEth are promising markers for alcohol-related pancreatitis, but they have not yet been validated in larger clinical studies.
Where this research is happening
Scottsdale, United States
- Mayo Clinic Arizona — Scottsdale, United States (Active)
Researchers
- Principal investigator: Singh, Vijay Prem — Mayo Clinic Arizona
- Study coordinator: Singh, Vijay Prem
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.