Finding biomarkers to predict severe leptospirosis and its long-term effects
Identification of predictive biomarkers for severe acute leptospirosis and its long-term sequelae
['FUNDING_R01'] · CHULALONGKORN UNIVERSITY · NIH-10895606
This study is looking for ways to find signs in blood tests that can help doctors predict how serious leptospirosis might be for patients, so they can provide better care and support for those at risk of severe illness.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CHULALONGKORN UNIVERSITY (nih funded) |
| Locations | 1 site (Bangkok, THAILAND) |
| Trial ID | NIH-10895606 on ClinicalTrials.gov |
What this research studies
This research investigates how to identify biomarkers that can predict the severity of leptospirosis, a serious infectious disease. By analyzing blood samples and clinical data from patients, researchers aim to develop methods to foresee which individuals are at risk of severe complications. The study employs advanced machine learning techniques to refine the identification of these biomarkers, which could lead to better patient management and outcomes. The research will utilize existing patient samples and recruit new participants for comprehensive analysis.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with leptospirosis, particularly those experiencing severe symptoms.
Not a fit: Patients with mild leptospirosis or those who have not been diagnosed with the disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier interventions for patients at risk of severe leptospirosis, potentially reducing mortality and long-term health complications.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for infectious diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
Bangkok, THAILAND
- CHULALONGKORN UNIVERSITY — Bangkok, THAILAND (ACTIVE)
Researchers
- Principal investigator: SRISAWAT, NATTACHAI — CHULALONGKORN UNIVERSITY
- Study coordinator: SRISAWAT, NATTACHAI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.