Finding biomarkers to predict outcomes in children with Multisystem Inflammatory Syndrome related to COVID-19
Identifying biomarker signatures of prognostic value for Multisystem Inflammatory Syndrome in Children (MIS-C)
This study is looking at how certain biological markers in kids and young adults can help doctors understand the risk of serious complications from Multisystem Inflammatory Syndrome (MIS-C) after COVID-19, so they can make better treatment choices.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Connecticut Children's Medical Center NIH-funded |
| Lab location | 1 site (Hartford, United States) |
| Project ID | NIH-10847825 on NIH RePORTER |
What this research studies
This research investigates how certain biological markers can help predict the severity of Multisystem Inflammatory Syndrome in Children (MIS-C) that may arise after COVID-19 infection. By analyzing samples from children and young adults with varying degrees of COVID-19 severity, the study aims to identify specific biomarkers that indicate a higher risk of severe complications. The approach includes advanced techniques like Grating-Coupled Fluorescence Plasmonic (GCFP) and flow cytometry to gather detailed immunological and molecular data. This information could ultimately guide treatment decisions and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are children and young adults under 21 years old who have been diagnosed with COVID-19, particularly those exhibiting symptoms of MIS-C.
Not a fit: Patients who are over 21 years old or those who have not been infected with COVID-19 are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better risk assessment and targeted treatments for children at risk of severe complications from COVID-19.
How similar studies have performed: Other research has shown promise in identifying biomarkers for various conditions, suggesting that this approach could yield valuable insights for MIS-C as well.
Where this research is happening
Hartford, United States
- Connecticut Children's Medical Center — Hartford, United States (Active)
Researchers
- Principal investigator: Salazar, Juan C — Connecticut Children's Medical Center
- Study coordinator: Salazar, Juan C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.