Finding biomarkers to predict outcomes in children with Multisystem Inflammatory Syndrome related to COVID-19

Identifying biomarker signatures of prognostic value for Multisystem Inflammatory Syndrome in Children (MIS-C)

NIH-funded research Connecticut Children's Medical Center · NIH-10733688

This study is looking at how specific markers in the blood can help doctors understand which kids and young adults with COVID-19 might get sicker from Multisystem Inflammatory Syndrome, so they can provide better care and treatment.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionConnecticut Children's Medical Center NIH-funded
Lab location1 site (Hartford, United States)
Project IDNIH-10733688 on NIH RePORTER

What this research studies

This research investigates how certain biological markers can help predict the severity of Multisystem Inflammatory Syndrome in children who have been infected with SARS-CoV-2. By analyzing blood samples and using advanced testing methods, the study aims to identify which children are at higher risk for severe complications. The goal is to improve diagnosis and treatment strategies for affected children, ultimately enhancing their care and outcomes. Participants will include children and young adults under 21 years old who have experienced COVID-19 symptoms.

Who could benefit from this research

Good fit: Ideal candidates for this research are children and young adults under 21 years old who have been diagnosed with COVID-19 and may be at risk for developing Multisystem Inflammatory Syndrome.

Not a fit: Patients who are over 21 years old or those who have not been infected with SARS-CoV-2 are unlikely to benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better risk assessment and targeted treatments for children suffering from severe COVID-19 complications.

How similar studies have performed: Other research has shown promise in identifying biomarkers for various diseases, suggesting that this approach could yield valuable insights for MIS-C as well.

Where this research is happening

Hartford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.