Finding biomarkers to predict outcomes in children with Multisystem Inflammatory Syndrome related to COVID-19
Official title: Identifying biomarker signatures of prognostic value for Multisystem Inflammatory Syndrome in Children (MIS-C)
Funded at Connecticut Children's Medical Center · NIH-10733688 · Data updated 2026-11-12
This study is looking at how specific markers in the blood can help doctors understand which kids and young adults with COVID-19 might get sicker from Multisystem Inflammatory Syndrome, so they can provide better care and treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Connecticut Children's Medical Center NIH-funded |
| Lab location | 1 site (Hartford, United States) |
| Project start | January 1, 2021 |
| Project end | November 30, 2025 |
| Funding year | 2023 |
| Award (this year) | $1,637,600 |
| NIH project number | 4R33HD105613-03 |
| Project ID | NIH-10733688 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children and young adults under 21 years old who have been diagnosed with COVID-19 and may be at risk for developing Multisystem Inflammatory Syndrome.
✕Less likely to help
Patients who are over 21 years old or those who have not been infected with SARS-CoV-2 are unlikely to benefit from this research.
What this research studies
This research investigates how certain biological markers can help predict the severity of Multisystem Inflammatory Syndrome in children who have been infected with SARS-CoV-2. By analyzing blood samples and using advanced testing methods, the study aims to identify which children are at higher risk for severe complications. The goal is to improve diagnosis and treatment strategies for affected children, ultimately enhancing their care and outcomes. Participants will include children and young adults under 21 years old who have experienced COVID-19 symptoms.
Why it matters
Potential benefit: If successful, this research could lead to better risk assessment and targeted treatments for children suffering from severe COVID-19 complications.
How similar studies have gone: Other research has shown promise in identifying biomarkers for various diseases, suggesting that this approach could yield valuable insights for MIS-C as well.
Where this research is happening
-
Connecticut Children's Medical Center
Hartford, United States Active
Researchers
- Principal investigator: Salazar, Juan C — Connecticut Children's Medical Center
- Study coordinator: Salazar, Juan C
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Finding biomarkers to predict outcomes in children with Multisystem Inflammatory Syndrome related to COVID-19
This study is looking at how certain biological markers in kids and young adults can help doctors understand the risk of serious complications from Multisystem Inflammatory Syndrome (MIS-C) after COVID-19, so they can make better treatment choices.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.