Finding biomarkers related to brain injury and resilience in HIV-1 and methamphetamine users
Identification of Biomarkers of CNS injury and resilience related to HIV-1 and Methamphetamine
This study is looking at how methamphetamine use impacts the brain in people living with HIV-1, aiming to find signs that show brain damage or strength, so we can better understand and treat brain-related issues that can come with these conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10441280 on NIH RePORTER |
What this research studies
This research investigates how methamphetamine use affects the brain in individuals with HIV-1, particularly focusing on identifying biomarkers that indicate brain injury and resilience. By examining the neurotoxic effects of both methamphetamine and HIV, the study aims to uncover valuable insights that could lead to better clinical assessments and treatments. The research will involve screening a wide range of clinical and research biomarkers to validate those that can effectively detect brain and peripheral complications associated with these conditions. Ultimately, the goal is to improve understanding and management of HIV-related neurocognitive disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV-1 who also have a history of methamphetamine use.
Not a fit: Patients who do not have HIV-1 or a history of methamphetamine use may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for individuals affected by HIV and methamphetamine use.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for neurocognitive disorders related to HIV, but this specific approach combining methamphetamine and HIV is relatively novel.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Iudicello, Jennifer E — University of California, San Diego
- Study coordinator: Iudicello, Jennifer E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.