Finding biomarkers in bodily fluids for Parkinson's disease and Lewy body dementia
Identification and Verification of S-Nitrosylated Proteins in Bodily Fluids as Biomarkers for Parkinson's Disease and Lewy Body Dementia
This study is looking for certain proteins in your body fluids that could help spot Parkinson's disease and Lewy body dementia early on, even before you notice any symptoms, so that doctors can diagnose and track the disease better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Scripps Research Institute, the NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10220628 on NIH RePORTER |
What this research studies
This research aims to identify specific proteins in bodily fluids that can serve as biomarkers for Parkinson's disease (PD) and Lewy body dementia (LBD). By focusing on the S-nitrosylation of proteins, the study seeks to understand how these changes can indicate the presence of these neurodegenerative diseases before symptoms appear. The approach involves analyzing the relationship between these biomarkers and the progression of cognitive and motor symptoms in patients. This could lead to earlier diagnosis and better monitoring of disease severity.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for Parkinson's disease or Lewy body dementia, particularly those with early symptoms or family history of these conditions.
Not a fit: Patients who are already diagnosed with advanced stages of Parkinson's disease or Lewy body dementia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enable earlier detection and more effective management of Parkinson's disease and Lewy body dementia.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for neurodegenerative diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
La Jolla, United States
- Scripps Research Institute, the — La Jolla, United States (Active)
Researchers
- Principal investigator: Nakamura, Tomohiro — Scripps Research Institute, the
- Study coordinator: Nakamura, Tomohiro
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.