Finding better ways to screen for tuberculosis in Brazilian prisons
Identifying effective and efficient approaches to tuberculosis screening in Brazilianprisons
['FUNDING_CAREER'] · BOSTON UNIVERSITY MEDICAL CAMPUS · NIH-11001464
This study is looking to find better ways to detect tuberculosis in prisoners in Brazil who can't provide the usual samples for testing, using a new method that captures bacteria from their breath, to help ensure that everyone gets the care they need.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON UNIVERSITY MEDICAL CAMPUS (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11001464 on ClinicalTrials.gov |
What this research studies
This research aims to improve tuberculosis detection among prisoners in Brazil, a high-risk group with a significant disease burden. The project will assess the prevalence of undiagnosed tuberculosis in inmates who cannot provide sputum samples, which are typically required for diagnosis. It will also evaluate a new diagnostic tool called the Mask Aerosol Sampling system (MASS) that captures exhaled bacteria, and develop cost-effective screening algorithms to enhance case detection. By focusing on non-sputum-based methods, the research seeks to address the limitations of current diagnostic practices in this vulnerable population.
Who could benefit from this research
Good fit: Ideal candidates for this research are incarcerated individuals in Brazilian prisons who are at high risk for tuberculosis and unable to provide sputum samples.
Not a fit: Patients outside of the prison system or those who can provide sputum samples may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and treatment of tuberculosis in Brazilian prisons, ultimately reducing transmission and improving health outcomes for inmates.
How similar studies have performed: Previous studies have shown success in tuberculosis screening in high-risk populations, but the specific approach using the MASS tool is novel.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON UNIVERSITY MEDICAL CAMPUS — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MARTINEZ, LEONARDO — BOSTON UNIVERSITY MEDICAL CAMPUS
- Study coordinator: MARTINEZ, LEONARDO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus, burden of disease