Finding better ways to prevent malaria during pregnancy in Uganda
Optimal chemopreventive regimens to prevent malaria and improve birth outcomes in Uganda
This study is looking at the best ways to prevent malaria in pregnant women in Uganda, comparing a new treatment to the usual one to see which helps keep moms and babies healthier.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10813876 on NIH RePORTER |
What this research studies
This research investigates effective methods to prevent malaria in pregnant women in Uganda, where malaria poses significant health risks. The study focuses on comparing the efficacy of different preventive treatments, particularly looking at the use of dihydroartemisin-piperaquine (DP) versus the standard treatment. By assessing the impact of these treatments on maternal health and birth outcomes, the research aims to identify strategies that can reduce complications such as miscarriages and low birth weight. Patients may be involved in trials that evaluate these new treatment regimens.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women living in malaria-endemic regions of Uganda.
Not a fit: Patients who are not pregnant or those living outside malaria-endemic areas may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved health outcomes for pregnant women and their babies by reducing the incidence of malaria-related complications.
How similar studies have performed: Previous research has shown promising results with similar approaches, particularly the use of artemisinin-based combination therapies in malaria prevention.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Dorsey, Matthew G — University of California, San Francisco
- Study coordinator: Dorsey, Matthew G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.