Finding better ways to predict survival in patients with pulmonary arterial hypertension.
Identifying Clinical Markers of Right Ventricular Adaptation to Improve Survival Predictions in Pulmonary Arterial Hypertension
['FUNDING_FELLOWSHIP'] · JOHNS HOPKINS UNIVERSITY · NIH-10998296
This study is looking to help doctors better predict how long patients with pulmonary arterial hypertension (PAH) might live by finding simple signs that show how well the heart is coping with the condition, using information from over 100 patients who have had heart tests.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10998296 on ClinicalTrials.gov |
What this research studies
This research focuses on improving survival predictions for patients with pulmonary arterial hypertension (PAH) by identifying clinical markers that reflect how well the right ventricle adapts to increased pressures in the pulmonary arteries. The study will analyze data from over 100 patients who have undergone various heart assessments, including right heart catheterization and echocardiograms. By exploring accessible metrics that can serve as indicators of right ventricular adaptation, the research aims to enhance existing clinical risk scores and provide more accurate prognoses for patients with PAH.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with pulmonary arterial hypertension who have undergone or are scheduled for heart assessments.
Not a fit: Patients who do not have pulmonary arterial hypertension or those with advanced heart failure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate survival predictions for patients with pulmonary arterial hypertension, potentially guiding better treatment decisions.
How similar studies have performed: Previous research has shown promise in using similar metrics to predict outcomes in heart conditions, suggesting that this approach could yield valuable insights.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ROSEN, DARIN — JOHNS HOPKINS UNIVERSITY
- Study coordinator: ROSEN, DARIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.