Finding better ways to manage chronic pain in cancer survivors

Better options for chronic cancer pain: a SMART study

NIH-funded research Veterans Health Administration · NIH-11054164

This study is looking for ways to help cancer survivors who are using opioids for long-term pain relief manage their pain better, by trying out different treatment methods to see if they can reduce opioid use without making pain worse.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVeterans Health Administration NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11054164 on NIH RePORTER

What this research studies

This research investigates how to help cancer survivors who are on long-term opioid therapy manage their chronic pain more effectively. It focuses on two approaches: multimodal pain care and buprenorphine rotation, which have shown promise in veterans with musculoskeletal pain but have not been tested in cancer survivors. The study aims to determine which of these strategies, or a combination of them, can reduce opioid use without increasing pain levels over a period of 6 to 9 months. By identifying the best treatment options, the research seeks to improve pain management for cancer survivors and reduce their reliance on opioids.

Who could benefit from this research

Good fit: Ideal candidates for this research are cancer survivors who are currently on long-term opioid therapy for chronic pain.

Not a fit: Patients who are not on long-term opioid therapy or those without chronic pain related to cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide safer and more effective pain management options for cancer survivors, reducing their dependence on opioids.

How similar studies have performed: Previous research has shown success with multimodal pain management strategies in veterans, indicating potential for similar outcomes in cancer survivors.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions addictive disorderanti-cancer therapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.