Finding better ways to detect worsening glaucoma

Detection of Disease Progression in Advanced Glaucoma

NIH-funded research University of California Los Angeles · NIH-10798326

This study is looking at whether measuring the thickness of certain eye cells can help doctors spot worsening glaucoma earlier and more accurately, which could lead to better care for patients dealing with this serious eye condition.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-10798326 on NIH RePORTER

What this research studies

This research focuses on improving the detection of disease progression in patients with advanced glaucoma, a condition that can lead to blindness. The team will investigate whether measuring the thickness of the macular retinal ganglion cell and axonal complex can provide earlier and more accurate indications of visual field deterioration compared to traditional methods. By analyzing data from glaucoma patients over five years, the researchers aim to validate their new approach against existing measures. This could lead to more effective monitoring and treatment strategies for those affected by advanced glaucoma.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with advanced glaucoma who are at risk of vision loss.

Not a fit: Patients with early-stage glaucoma or those without a diagnosis of glaucoma may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier detection of glaucoma progression, potentially preserving vision for patients.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for glaucoma detection, suggesting that this approach could build on existing knowledge.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DisorderDisease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.