Finding better ways to assess nerve damage in early multiple sclerosis
Improving the Assessment of Myelin and Axonal Integrity in Early Multiple Sclerosis
This study is looking to make MRI scans better at spotting nerve damage in people with multiple sclerosis, helping doctors understand how the disease is affecting you and what might happen in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10889036 on NIH RePORTER |
What this research studies
This research aims to improve the assessment of nerve damage caused by multiple sclerosis (MS) by developing new magnetic resonance imaging (MRI) techniques. The focus is on identifying specific MRI biomarkers that can detect myelin and axonal injury, which are critical for understanding disease progression and patient outcomes. By using advanced imaging methods, the study seeks to provide more accurate predictions of how MS will affect individuals over time. Patients diagnosed with MS will be monitored to evaluate the effectiveness of these new imaging techniques.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with early-stage multiple sclerosis.
Not a fit: Patients with advanced multiple sclerosis or those without a confirmed diagnosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate assessments of nerve damage in MS, potentially improving treatment strategies and patient outcomes.
How similar studies have performed: Previous research has shown promise in developing MRI techniques for assessing neurodegeneration, but this specific approach is considered novel.
Where this research is happening
Nashville, United States
- Veterans Health Administration — Nashville, United States (Active)
Researchers
- Principal investigator: Bagnato, Francesca Rosaria — Veterans Health Administration
- Study coordinator: Bagnato, Francesca Rosaria
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.