Finding better treatments for head and neck cancer
Yale Head and Neck Cancer SPORE: Overcoming Treatment Resistance in Head and Neck Cancer
This study at Yale is looking for better ways to treat head and neck cancer, especially for those tough cases that don’t respond well to current treatments, so they can help patients live healthier and longer lives.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11082653 on NIH RePORTER |
What this research studies
This research focuses on improving treatment options for head and neck squamous cell carcinoma (HNSCC), a common and often deadly cancer. The team at Yale is investigating why some tumors resist current therapies, including immunotherapy and targeted treatments. They aim to develop new strategies to overcome this resistance, particularly for HPV-negative tumors, which are more challenging to treat. By combining different therapeutic approaches, they hope to enhance patient outcomes and reduce the recurrence of cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients diagnosed with head and neck squamous cell carcinoma, particularly those with HPV-negative tumors or those who have experienced treatment resistance.
Not a fit: Patients with other types of cancers or those whose head and neck cancer is not resistant to current therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with head and neck cancer, potentially improving survival rates and quality of life.
How similar studies have performed: Previous research has shown promise in overcoming treatment resistance in various cancers, suggesting that this approach could yield significant advancements in head and neck cancer treatment.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Burtness, Barbara — Yale University
- Study coordinator: Burtness, Barbara
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.