Finding better treatments for chronic Chagas disease

New Treatments for Chronic Chagas Disease

['FUNDING_OTHER'] · UNIVERSITY OF TEXAS EL PASO · NIH-10749029

This study is looking to create a better treatment for chronic Chagas disease by combining a vaccine with special medications, aiming to help those who are struggling with this condition feel better and improve their health.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF TEXAS EL PASO (nih funded)
Locations1 site (EL PASO, UNITED STATES)
Trial IDNIH-10749029 on ClinicalTrials.gov

What this research studies

This research aims to develop a new treatment for chronic Chagas disease, a condition caused by the parasite Trypanosoma cruzi, which affects millions globally. The current treatments are only partially effective, especially for chronic cases. The researchers propose a novel approach that combines a vaccine with specific drug candidates to enhance treatment efficacy. By using a combination of immunotherapy and targeted drugs, they hope to achieve better outcomes for patients suffering from this neglected tropical disease.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with chronic Chagas disease, particularly those who have not responded well to existing treatments.

Not a fit: Patients who are in the acute phase of Chagas disease or those who do not have a confirmed diagnosis of chronic Chagas disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a more effective treatment for chronic Chagas disease, improving the quality of life for affected patients.

How similar studies have performed: Previous research has shown promise in using combined therapies for treating similar parasitic infections, indicating potential for success in this novel approach.

Where this research is happening

EL PASO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.