Finding better, affordable HIV care for low-resource countries
Optimizing HIV Care in Less Developed Countries
['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-11145889
This project uses computer modeling to find HIV testing, treatment, and prevention approaches that help people with HIV the most while fitting tight budgets in low-resource countries.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11145889 on ClinicalTrials.gov |
What this research studies
This project uses computer simulations to compare different HIV testing, treatment, and prevention options so programs in poorer countries can get the most health benefit for their money. The team will expand an existing simulation (CEPAC-I) to include new drugs, prevention tools, and realistic local budget limits. They will combine clinical outcomes, costs, and guideline scenarios to predict deaths averted, infections prevented, and costs per patient. The goal is to produce clear guidance that health programs and policymakers can use to reach more people with effective care.
Who could benefit from this research
Good fit: People living with HIV or at high risk in low- and middle-income countries, especially those served by programs with limited budgets, are the main populations this work aims to help.
Not a fit: People without HIV or those receiving care in high-resource settings with ample funding are unlikely to see direct benefits from this modeling work.
Why it matters
Potential benefit: If successful, this work could help health programs in low-resource countries choose affordable HIV strategies that increase treatment coverage and reduce deaths.
How similar studies have performed: Previous CEPAC and other cost-effectiveness models have informed national and global HIV policy, so the approach is established though it will test new scenarios and parameters.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FREEDBERG, KENNETH ALAN — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: FREEDBERG, KENNETH ALAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome, Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome, Acquired Immunodeficiency Syndrome Virus